Supplementation with low doses of vitamin E protects LDL from lipid peroxidation in men and women.

@article{Princen1995SupplementationWL,
  title={Supplementation with low doses of vitamin E protects LDL from lipid peroxidation in men and women.},
  author={Hans M G Princen and Wim van Duyvenvoorde and Rien Buytenhek and Arnoud van der Laarse and Geert van Poppel and Jan A Gevers Leuven and Victor W. M. van Hinsbergh},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1995},
  volume={15 3},
  pages={325-33}
}
There is accumulating evidence that oxidative modification of LDL is an important step in the process of atherogenesis and that antioxidants may protect LDL from oxidation. We and others have previously shown that ingestion of pharmacological doses of the antioxidant D,L-alpha-tocopherol (vitamin E), far above the recommended daily intake (ie, 12 to 15 IU/d for adults), increases the oxidation resistance of LDL. In this study, we ascertained the minimal supplementary dose of vitamin E necessary… CONTINUE READING
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