Supplementation with a complex of active nutrients improved dermal and epidermal characteristics in skin equivalents generated from fibroblasts from young or aged donors

@article{Lacroix2006SupplementationWA,
  title={Supplementation with a complex of active nutrients improved dermal and epidermal characteristics in skin equivalents generated from fibroblasts from young or aged donors},
  author={Sophie D Lacroix and Charbel Bouez and Sandrine Vidal and Val{\'e}rie Cenizo and Corinne Reymermier and Virginie Justin and Jana Vi{\vc}anov{\'a} and Odile Damour},
  journal={Biogerontology},
  year={2006},
  volume={8},
  pages={97-109}
}
Cultured skin equivalent (SE, Mimeskin®) was generated by co-culturing skin fibroblasts and keratinocytes on a collagen-glycosaminoglycan-chitosan dermal substrate. In order to examine donor age effect, fibroblasts from 19- (young) or 49- (aged) year-old females were used. Culture medium was supplemented with nutrients complex containing soy extract, tomato extract, grape seed extract, white tea extract, sodium ascorbate, tocopherol acetate, zinc gluconate and BioMarine™ complex. Epidermal and… CONTINUE READING