Supplementation of glycosaminoglycans and their precursors in osteoarthritis versus diet modification

@article{Jargin2012SupplementationOG,
  title={Supplementation of glycosaminoglycans and their precursors in osteoarthritis versus diet modification},
  author={Sergei V. Jargin},
  journal={International Journal of Rheumatic Diseases},
  year={2012},
  volume={15}
}
  • S. Jargin
  • Published 1 June 2012
  • Medicine
  • International Journal of Rheumatic Diseases
Dear Editor, Chondroitin sulfate (CS) is a glycosaminoglycan (GAG) and glucosamine (Ga) is an aminosaccharide acting as a substrate for biosynthesis of GAG. CS undergoes hydrolysis in the intestine; being administered orally, it can also be regarded as a source of precursors for GAG. Hyaluronic acid (HA) is a GAG used for intra-articular injections. These substances are applied for treatment of osteoarthritis and are sometimes named chondroprotectives. Evidence in favor of their effectiveness… Expand
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