Supplemental arginine vasopressin during the resuscitation of severe hemorrhagic shock preserves renal mitochondrial function

@inproceedings{Sims2017SupplementalAV,
  title={Supplemental arginine vasopressin during the resuscitation of severe hemorrhagic shock preserves renal mitochondrial function},
  author={Carrie A Sims and Guan Yuxia and Khushboo Singh and Evan C Werlin and Patrick M. Reilly and Joseph A. Baur},
  booktitle={PloS one},
  year={2017}
}
Arginine vasopressin (AVP), a hormone secreted by the posterior pituitary, plays a vital role in maintaining vasomotor tone during acute blood loss. We hypothesized that decompensated hemorrhagic shock is associated with decreased AVP stores and supplementation during resuscitation would improve both blood pressure and renal function. Using a decompensated hemorrhagic shock model, male Long-Evans rats were bled to mean arterial blood pressure (MAP) of 40mmHg and maintained until the MAP could… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS

References

Publications referenced by this paper.
Showing 1-10 of 42 references

Vasopressin infsuion with smallvolume fluid resuscitation during hemorrhagic shock promotes hemodynamic stbility and survival in swine

  • RJ Gazmuri, K. Whitehouse, K. Whittinghill, A. Baetiong, J Radhakrishnan
  • PLOSOne
  • 2015

Similar Papers

Loading similar papers…