Supplement 1 Mathematical Model

  title={Supplement 1 Mathematical Model},
    The transport rate v of a substrate x mediated by a transporter is in general described by Michaelis-Menten kinetics (Stein, 1990), i.e. v = v max x Km+x. Since the substrate concentrations in our experiments are smaller, respectively in the order of the Michaelis-Menten constants of OATP1B3 and ABCC2 (Letschert et al., 2004; Cui et al., 2001), we… CONTINUE READING