Superparamagnetic iron oxide does not affect the viability and function of adipose-derived stem cells, and superparamagnetic iron oxide-enhanced magnetic resonance imaging identifies viable cells.

@article{Wang2009SuperparamagneticIO,
  title={Superparamagnetic iron oxide does not affect the viability and function of adipose-derived stem cells, and superparamagnetic iron oxide-enhanced magnetic resonance imaging identifies viable cells.},
  author={Lei Wang and Jixian Deng and Jian Wang and Bo Xiang and Tonghua Yang and Marco Gruwel and Tarek Kashour and Boguslaw Tomanek and Randy Summer and Darren M Freed and Davinder S Jassal and Guangping Dai and Miriam Glogowski and Roxanne Deslauriers and Rakesh Christopher Arora and Ganghong Tian},
  journal={Magnetic resonance imaging},
  year={2009},
  volume={27 1},
  pages={108-19}
}
The objectives of this study were (1) to determine whether superparamagnetic iron oxide (SPIO) affects viability, transdifferentiation potential and cell-factor secretion of adipose-derived stem cells (ASCs); and (2) to determine whether SPIO-enhanced magnetic resonance (MR) imaging highlights living stem cells. Rat ASCs were incubated in SPIO-containing cell culture medium for 2 days. The SPIO-treated ASCs were then subjected to adipogenic, osteogenic and myogenic transdifferentiation… CONTINUE READING

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