Superoxide stimulates IP3-induced Ca2+ release from vascular smooth muscle sarcoplasmic reticulum.

@article{Suzuki1992SuperoxideSI,
  title={Superoxide stimulates IP3-induced Ca2+ release from vascular smooth muscle sarcoplasmic reticulum.},
  author={Y J Suzuki and George D. Ford},
  journal={The American journal of physiology},
  year={1992},
  volume={262 1 Pt 2},
  pages={
          H114-6
        }
}
Reactive oxygen intermediates (ROI) have been implicated in a variety of pathophysiological conditions, and vascular smooth muscle may be a site of damage in such oxygen toxicity. Mechanisms of the effects of these intermediates on vascular smooth muscle at the cellular level, however, have not been well studied. We have previously shown that xanthine oxidase (XO)-generated superoxide radicals (O2-.) inhibited the Ca(2+)-adenosine triphosphatase of vascular smooth muscle sarcoplasmic reticulum… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 53 CITATIONS, ESTIMATED 47% COVERAGE

Exercise-induced protection against myocardial apoptosis and necrosis: MnSOD, calcium-handling proteins, and calpain.

  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2008
VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1997
2018

CITATION STATISTICS

  • 2 Highly Influenced Citations