Superoxide radical anions protect enkephalin from oxidation if the amine group is blocked.

Abstract

The pentapeptide methionine-enkephalin (Met-enk) is a natural opiate that inhibits signals of pain. The N-terminal tyrosyl residue is important in the recognition of the peptide by its receptor. In oxidative stress, this residue can be oxidized by reactive oxygen species. The one-electron oxidation of Met-enk and of tert-butoxycarbonyl-methionine-enkephalin… (More)

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@article{Mozziconacci2007SuperoxideRA, title={Superoxide radical anions protect enkephalin from oxidation if the amine group is blocked.}, author={Olivier Mozziconacci and Jacek Mirkowski and Filippo Rusconi and Pascal Pernot and Krzysztof Bobrowski and Chantal Hou{\'e}e-L{\'e}vin}, journal={Free radical biology & medicine}, year={2007}, volume={43 2}, pages={229-40} }