Superoxide dismutases: ancient enzymes and new insights.

  title={Superoxide dismutases: ancient enzymes and new insights.},
  author={Anne-Frances Miller},
  journal={FEBS letters},
  volume={586 5},
Superoxide dismutases (SODs) catalyze the de toxification of superoxide. SODs therefore acquired great importance as O(2) became prevalent following the evolution of oxygenic photosynthesis. Thus the three forms of SOD provide intriguing insights into the evolution of the organisms and organelles that carry them today. Although ancient organisms employed Fe-dependent SODs, oxidation of the environment made Fe less bio-available, and more dangerous. Indeed, modern lineages make greater use of… CONTINUE READING
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