Superoxide dismutase influences the virulence of Cryptococcus neoformans by affecting growth within macrophages.

@article{Cox2003SuperoxideDI,
  title={Superoxide dismutase influences the virulence of Cryptococcus neoformans by affecting growth within macrophages.},
  author={Gary Matthew Cox and Thomas Stephen Harrison and Henry C McDade and Carlos Pelleschi Taborda and Garrett Heinrich and Arturo Casadevall and John R Perfect},
  journal={Infection and immunity},
  year={2003},
  volume={71 1},
  pages={173-80}
}
Superoxide dismutase (SOD) is an enzyme that converts superoxide radicals into hydrogen peroxide and molecular oxygen and has been shown to contribute to the virulence of many human-pathogenic bacteria through its ability to neutralize toxic levels of reactive oxygen species generated by the host. SOD has also been speculated to be important in the pathogenesis of fungal infections, but the role of this enzyme has not been rigorously investigated. To examine the contribution of SOD to the… CONTINUE READING

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