Superoxide anion production by neutrophils is associated with prevalent clinical manifestations in systemic lupus erythematosus

@article{Alves2007SuperoxideAP,
  title={Superoxide anion production by neutrophils is associated with prevalent clinical manifestations in systemic lupus erythematosus},
  author={Celene M. O. S. Alves and Cleni Mara Marzocchi-Machado and Paulo Louzada-J{\'u}nior and Ana Elisa Caleiro Seixas Azzolini and Ana Cristina Morseli Polizello and Ivan Fiore de Carvalho and Yara Maria Lucisano-Valim},
  journal={Clinical Rheumatology},
  year={2007},
  volume={27},
  pages={701-708}
}
To determine the relation between neutrophil function and the clinical characteristics of systemic lupus erythematosus (SLE), the superoxide anion ( $${\text{O}}_2^ - $$ ) production by neutrophils, mediated by FcγR and FcγR/CR cooperation, was studied in 64 SLE patients classified according to their prevalent clinical manifestations. Three clinically distinct patterns were designated: (1) manifestations associated with the occurrence of cytotoxic antibodies (SLE-I group); (2) manifestations… CONTINUE READING