Superovulation of female mice delays embryonic and fetal development.

@article{Auwera2001SuperovulationOF,
  title={Superovulation of female mice delays embryonic and fetal development.},
  author={Ingrid van der Auwera and Thomas D'hooghe},
  journal={Human reproduction},
  year={2001},
  volume={16 6},
  pages={1237-43}
}
Mouse and human embryos, cultured in vitro, undergo a delay in development compared with those grown in vivo. This delay can be caused by suboptimal culture conditions, but possible influences of ovarian stimulation cannot be excluded. The objective of this study was to test the hypothesis that both in vitro and in vivo, preimplantation embryonic development and postimplantation fetal development are impaired in superovulated female mice when compared with naturally cycling controls. A delay in… CONTINUE READING
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