Supernumerary marker chromosome 15 in a male with azoospermia and open bite deformity.

@article{Koc2009SupernumeraryMC,
  title={Supernumerary marker chromosome 15 in a male with azoospermia and open bite deformity.},
  author={A. Gokce Koc and Simone Onur and Mehmet Ali Erg{\"u}n and Emriye Ferda Perçin},
  journal={Asian journal of andrology},
  year={2009},
  volume={11 5},
  pages={617-22}
}
Supernumerary marker chromosome 15 (sSMC[15]) is the most frequent marker chromosome, and it is generally regarded as unimportant if it does not contain the Prader-Willi/Angelman syndrome critical region (PWACR). The clinical importance of the larger markers in association with the critical region is mentioned in almost all reports related to marker chromosome 15, and smaller markers are solely associated with minor dysmorphic features, azoospermia and recurrent miscarriages. However, these… CONTINUE READING