Superiority of network motifs over optimal networks and an application to the revelation of gene network evolution

Abstract

MOTIVATION Estimating the network of regulative interactions between genes from gene expression measurements is a major challenge. Recently, we have shown that for gene networks of up to around 35 genes, optimal network models can be computed. However, even optimal gene network models will in general contain false edges, since the expression data will not… (More)
DOI: 10.1093/bioinformatics/bth484

Topics

12 Figures and Tables