Superior chronic tolerability of adjunctive modafinil compared to pramipexole in treatment-resistant bipolar disorder.

@article{Dellosso2013SuperiorCT,
  title={Superior chronic tolerability of adjunctive modafinil compared to pramipexole in treatment-resistant bipolar disorder.},
  author={Bernardo Dell'osso and Sara Timtim and Farnaz Hooshmand and Shefali Miller and Po Wen Wang and Shelley J Hill and Natalie Portillo and Terence A. Ketter},
  journal={Journal of affective disorders},
  year={2013},
  volume={150 1},
  pages={130-5}
}
BACKGROUND Suboptimal outcomes are common in bipolar disorder (BD) pharmacotherapy, and may be mitigated with novel adjunctive agents such as modafinil (a low-affinity dopamine transport inhibitor) and pramipexole (a dopamine D2/D3 receptor agonist). While uncontrolled long-term effectiveness data have been reported for these treatments, reports specifically assessing their comparative acute versus chronic tolerability in BD are lacking. Such information, particularly in relation to… CONTINUE READING
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2012b Use of Adjunctive Pramipexole in Bipolar Depression

  • B. Dell’Osso, T. A. Ketter
  • 2012
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