Superinfection exclusion in duck hepatitis B virus infection is mediated by the large surface antigen.

@article{Walters2004SuperinfectionEI,
  title={Superinfection exclusion in duck hepatitis B virus infection is mediated by the large surface antigen.},
  author={K Walters and Michael A. S. Joyce and William R. Addison and Karl P. Fischer and D. Lorne Tyrrell},
  journal={Journal of virology},
  year={2004},
  volume={78 15},
  pages={7925-37}
}
Superinfection exclusion is the phenomenon whereby a virus prevents the subsequent infection of an already infected host cell. The Pekin duck hepatitis B virus (DHBV) model was used to investigate superinfection exclusion in hepadnavirus infections. Superinfection exclusion was shown to occur both in vivo and in vitro with a genetically marked DHBV, DHBV-ClaI, which was unable to establish an infection in either DHBV-infected ducklings or DHBV-infected primary duck hepatocytes (PDHs). In… CONTINUE READING
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