Supercomputer simulations of platelet activation in blood plasma at multiple scales

Abstract

Thrombogenicity in cardiovascular devices and pathologies is associated with flow-induced shear stress activation of platelets resulting from pathological flow patterns. This platelet activation process poses a major modeling challenge as it covers disparate spatiotemporal scales, from flow down to cellular, to subcellular, and to molecular scales. This… (More)
DOI: 10.1109/HPCSim.2014.6903802

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