Superbases for organic synthesis

@article{Schlosser1988SuperbasesFO,
  title={Superbases for organic synthesis},
  author={M. Schlosser},
  journal={Pure and Applied Chemistry},
  year={1988},
  volume={60},
  pages={1627 - 1634}
}
  • M. Schlosser
  • Published 1988
  • Chemistry
  • Pure and Applied Chemistry
  • A review with 70 refs. LICKOR mixts. of organolithium reagents and bulky potassium alcoholates allow the smooth metalation and subsequent electrophilic substitution of low acidity hydrocarbons, in particular olefins. The allylpotassium intermediates exhibit peculiar conformational preferences which can be exploited in novel stereoselective carbon-carbon linking reactions. A few syntheses of simple natural products illustrate the method. A tentative explanation is given for the superior… CONTINUE READING
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    References

    SHOWING 1-8 OF 8 REFERENCES
    ) , 320 , Angew . Chem . In !
    • J . Am . Chem . Soc .
    • 1982
    By the way, the superbase also metalates N,N,N:N’-tetramethylethyleneamine (yields of derivatives up to 45%, L
    • Rothen, diploma work, Universitd de Lausanne,
    • 1984
    Haltermann, I
    • Chem. Soc
    • 1986
    Mcquilh, I
    • Chem. Soc., Chem. Commun
    • 1977