Superantigens and Streptococcal Toxic Shock Syndrome

  title={Superantigens and Streptococcal Toxic Shock Syndrome},
  author={Thomas Proft and Shiranee Sriskandan and Lily P. H. Yang and John D Fraser},
  booktitle={Emerging infectious diseases},
have been implicated with streptococcal toxic shock syndrome (STSS). We analyzed 19 acute-phase serum samples for mitogenic activity from patients with severe strepto-coccal disease. The serum samples from two patients in the acute phase of STSS showed strong proliferative activity. Streptococcal mitogenic exotoxin (SME) Z-1 and strep-tococcal pyrogenic exotoxin (SPE)-J were identified in one patient with peritonitis who recovered after 2 weeks in intensive care. SMEZ-16 was found in a second… CONTINUE READING
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