Superantigenic activity is responsible for induction of coronary arteritis in mice: an animal model of Kawasaki disease.

@article{Duong2003SuperantigenicAI,
  title={Superantigenic activity is responsible for induction of coronary arteritis in mice: an animal model of Kawasaki disease.},
  author={Trang T Duong and Earl D Silverman and Martindale V Bissessar and Rae S. M. Yeung},
  journal={International immunology},
  year={2003},
  volume={15 1},
  pages={
          79-89
        }
}
Kawasaki disease (KD) is a multisystem vasculitis and the leading cause of acquired heart disease in children of the developed world. Lactobacillus casei cell wall extract-induced coronary arteritis in mice mirrors KD in children. Here, we report that responses to L. casei cell wall extract possess all the hallmarks of a superantigen-mediated response: marked proliferation of naive T cells, non-classical major histocompatibility restriction with a hierarchy in the efficiency of different class… CONTINUE READING

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and clonal deletion in neonatal mice

  • J. Fraser, V. Arcus, P. Kong, E. Baker, T. Proft
  • 2000

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