SuperTarget goes quantitative: update on drug–target interactions

@inproceedings{Hecker2012SuperTargetGQ,
  title={SuperTarget goes quantitative: update on drug–target interactions},
  author={Nikolai Hecker and Jessica Ahmed and Joachim von Eichborn and Mathias Dunkel and Karel Macha and Andreas Eckert and Michael K. Gilson and Philip E. Bourne and Robert Preissner},
  booktitle={Nucleic Acids Research},
  year={2012}
}
There are at least two good reasons for the on-going interest in drug-target interactions: first, drug-effects can only be fully understood by considering a complex network of interactions to multiple targets (so-called off-target effects) including metabolic and signaling pathways; second, it is crucial to consider drug-target-pathway relations for the identification of novel targets for drug development. To address this on-going need, we have developed a web-based data warehouse named… CONTINUE READING
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Target search results for VEGFR-1 and VEGFR-2 are added to the basket

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