Super-delta: a new differential gene expression analysis procedure with robust data normalization

Abstract

Normalization is an important data preparation step in gene expression analyses, designed to remove various systematic noise. Sample variance is greatly reduced after normalization, hence the power of subsequent statistical analyses is likely to increase. On the other hand, variance reduction is made possible by borrowing information across all genes… (More)
DOI: 10.1186/s12859-017-1992-2

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