Sunlight‐induced mutagenicity of a common sunscreen ingredient

@article{Knowland1993SunlightinducedMO,
  title={Sunlight‐induced mutagenicity of a common sunscreen ingredient},
  author={J. Knowland and E. Mckenzie and P. McHugh and N. A. Cridland},
  journal={FEBS Letters},
  year={1993},
  volume={324}
}
We have tested the mutagenicity of a UV‐B sunscreen ingredient called Padimate‐O or octyl dimethyl PABA, which, chemically speaking, is identical to an industrial chemical that generates free radicals when illuminated. It is harmless in the dark but mutagenic in sunlight, attacking DNA directly. A commercial sunscreen containing Padimate‐O behaves in the same way. UV‐A in sunlight also excites Padimate‐O, although less than UV‐B. Some related compounds, including a known carcinogen, behave… Expand
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