Sundowning and circadian rhythms in Alzheimer's disease.

@article{Volicer2001SundowningAC,
  title={Sundowning and circadian rhythms in Alzheimer's disease.},
  author={Ladislav Volicer and David G. Harper and Barbara C. Manning and Rachel Goldstein and Andrew Satlin},
  journal={The American journal of psychiatry},
  year={2001},
  volume={158 5},
  pages={
          704-11
        }
}
OBJECTIVE The goal of this study was to determine changes of circadian rhythms induced by Alzheimer's disease and to explore relationships among rhythm disturbances, sundowning, and sleep disturbances in patients with Alzheimer's disease. "Sundowning" is the occurrence or exacerbation of behavioral symptoms of Alzheimer's disease in the afternoon and evening. METHOD Circadian rhythms of core body temperature and motor activity were measured in 25 patients with diagnoses of probable Alzheimer… 

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