Sumatriptan plus metoclopramide in triptan-nonresponsive migraineurs.

  title={Sumatriptan plus metoclopramide in triptan-nonresponsive migraineurs.},
  author={Elliott A Schulman and Kathleen F Dermott},
  volume={43 7},
OBJECTIVES We evaluated the effectiveness of combination treatment using sumatriptan plus metoclopramide versus sumatriptan alone for the treatment of acute migraine. The patients who were treated had failed to respond to triptans in the past despite adequate doses on at least 2 separate trials of the same triptan or 2 trials involving different triptans. BACKGROUND There is limited evidence that dopaminergic antagonists may benefit the migraineur by relieving migraine pain and associated… CONTINUE READING