Sulpiride has an antiaggressive effect in mice without markedly depressing motor activity.

Abstract

The atypical neuroleptic, sulpiride is a selective D2 antagonist, having a preferential action on mesolimbic regions. The effects of acute and chronic treatment with sulpiride on aggressive behaviour in male mice were studied using an ethologically based analysis. It was hypothesized that sulpiride would diminish "threat" and "attack" but would not produce… (More)

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Cite this paper

@article{Redolat1991SulpirideHA, title={Sulpiride has an antiaggressive effect in mice without markedly depressing motor activity.}, author={Rosa Redolat and Paul Fredric Brain and V. M. Simon}, journal={Neuropharmacology}, year={1991}, volume={30 1}, pages={41-6} }