Sulpiride and Paroxetine in the Treatment of Chronic Tension‐Type Headache. An Explanatory Double‐Blind Trial

@article{Langemark1994SulpirideAP,
  title={Sulpiride and Paroxetine in the Treatment of Chronic Tension‐Type Headache. An Explanatory Double‐Blind Trial},
  author={Michael Langemark and Jes Olesen},
  journal={Headache: The Journal of Head and Face Pain},
  year={1994},
  volume={34}
}
  • M. Langemark, J. Olesen
  • Published 1 January 1994
  • Psychology, Geology, Medicine
  • Headache: The Journal of Head and Face Pain
SYNOPSIS 
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A critical clinical review of the use of selective serotonin reuptake inhibitors (SSRIs) in the management of pain suggests that there is little evidence for their replacement by SSRIs in pain management.
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  • R. Jensen
  • Medicine, Psychology
    Current treatment options in neurology
  • 2001
TLDR
The clinical presentation of tension-type headache is described, and treatment strategies for the acute episode as well as for the prophylaxis of chronic tension- type headache are summarized.
l‐5‐Hydroxytryptophan in the Prophylaxis of Chronic Tension‐type Headache: A Double‐Blind, Randomized, Placebo‐Controlled Study
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There was no statistically significant change in the number of days with headache or in headache intensity in the group treated with 5‐HTP, 300 mg per day; however, there was a significant decrease in the consumption of analgesics.
The Efficacy of Newer Antidepressants in the Treatment of Chronic Pain: A Review of Current Literature
TLDR
This article reviews the available publications, including placebo‐controlled trials, other outcome studies, and case reports, pertaining to the use of these medications for chronic pain, and makes generalizations regarding their use as analgesics.
Serotonin Reuptake Inhibitors and Their Role in Chronic Pain Management
TLDR
The scope of this chapter would be to update the knowledge regarding serotonin involving in pain pathways and to highlight the importance and contribution of serotonin reuptake inhibitors in the multimodal pain management schemes.
Central mechanisms in tension-type headaches
TLDR
From experimental research and clinical studies, it appears that myofascial nociception is important in episodic tension-type headache; however, central mechanisms (ie, central sensitization) are preponderant in the pathophysiology of the chronic form.
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