Sulpiride and Paroxetine in the Treatment of Chronic Tension‐Type Headache. An Explanatory Double‐Blind Trial

  title={Sulpiride and Paroxetine in the Treatment of Chronic Tension‐Type Headache. An Explanatory Double‐Blind Trial},
  author={Michael Langemark and Jes Olesen},
  journal={Headache: The Journal of Head and Face Pain},
  • M. Langemark, J. Olesen
  • Published 1 January 1994
  • Psychology, Geology, Medicine
  • Headache: The Journal of Head and Face Pain
Prophylactic Pharmacological Treatment of Chronic Daily Headache
All the prophylactic pharmacological treatments for chronic daily headache from the past decade are reviewed to review.
Sertraline versus amitriptyline in the prophylactic therapy of non-depressed chronic tension-type headache patients
It is suggested that both drugs were effective in the treatment of non-depressed patients with CTTH, but in comparison between groups, amitriptyline was more effective than sertraline.
The analgesic effects of selective serotonin reuptake inhibitors
  • A. Smith
  • Medicine
    Journal of psychopharmacology
  • 1998
A critical clinical review of the use of selective serotonin reuptake inhibitors (SSRIs) in the management of pain suggests that there is little evidence for their replacement by SSRIs in pain management.
Chronic Tension-Type Headache
Future advances in the treatment of this common disorder will depend on the performance of well designed trials of newer agents, making use of the newly established diagnostic criteria when identifying patients with chronic tension-type headache.
Tension-type headache
  • R. Jensen
  • Medicine, Psychology
    Current treatment options in neurology
  • 2001
The clinical presentation of tension-type headache is described, and treatment strategies for the acute episode as well as for the prophylaxis of chronic tension- type headache are summarized.
l‐5‐Hydroxytryptophan in the Prophylaxis of Chronic Tension‐type Headache: A Double‐Blind, Randomized, Placebo‐Controlled Study
There was no statistically significant change in the number of days with headache or in headache intensity in the group treated with 5‐HTP, 300 mg per day; however, there was a significant decrease in the consumption of analgesics.
The Efficacy of Newer Antidepressants in the Treatment of Chronic Pain: A Review of Current Literature
This article reviews the available publications, including placebo‐controlled trials, other outcome studies, and case reports, pertaining to the use of these medications for chronic pain, and makes generalizations regarding their use as analgesics.
Serotonin Reuptake Inhibitors and Their Role in Chronic Pain Management
The scope of this chapter would be to update the knowledge regarding serotonin involving in pain pathways and to highlight the importance and contribution of serotonin reuptake inhibitors in the multimodal pain management schemes.
Central mechanisms in tension-type headaches
From experimental research and clinical studies, it appears that myofascial nociception is important in episodic tension-type headache; however, central mechanisms (ie, central sensitization) are preponderant in the pathophysiology of the chronic form.


Antidepressants in the Management of Chronic Pain Syndromes
Antidepressants provide analgesia in conditions in which they have been used, and doses of heterocyclic antidepressants used for analgesia seem to be lower than those considered effective in the treatment of depression.
A Placebo-Controlled, Double-Blind, Cross-Over Trial of Flunarizine in Common Migraine
The effect of flunarizine increased during the 16-week treatment period and during the last four weeks the number of migraine attacks was reduced to 50% compared to the wash-out period.