Sulphonylurea-sensitive channels and NO-cGMP pathway modulate the heart rate response to vagal nerve stimulation in vitro.

Abstract

Sulphonylurea-sensitive K(+)channels (K(ATP)) have been implicated in the release of acetylcholine (ACh) from the vagus nerve in the heart. Our aim was to establish the functional significance of this and to test whether this modulation could interact with stimulation of the NO-cGMP pathway that facilitates the decrease in heart rate (HR) in response to… (More)

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Cite this paper

@article{Almond2000SulphonylureasensitiveCA, title={Sulphonylurea-sensitive channels and NO-cGMP pathway modulate the heart rate response to vagal nerve stimulation in vitro.}, author={Steve Almond and David J. Paterson}, journal={Journal of molecular and cellular cardiology}, year={2000}, volume={32 11}, pages={2065-73} }