Sulphonic acid strong cation-exchange restricted access columns in sample cleanup for profiling of endogenous peptides in multidimensional liquid chromatography. Structure and function of strong cation-exchange restricted access materials.

@article{Machtejevas2006SulphonicAS,
  title={Sulphonic acid strong cation-exchange restricted access columns in sample cleanup for profiling of endogenous peptides in multidimensional liquid chromatography. Structure and function of strong cation-exchange restricted access materials.},
  author={Egidijus Machtejevas and Renaud O Denoyel and Jorge Morales Meneses and Vilma Kudirkaitė and Brian Arthur Grimes and Dieter Dr. Lubda and Klaus K. Unger},
  journal={Journal of chromatography. A},
  year={2006},
  volume={1123 1},
  pages={
          38-46
        }
}
In this work, the pore structural parameters and size exclusion properties of LiChrospher strong cation-exchange and reverse phase restricted access materials (RAM) are analysed. The molecular weight size exclusion limit for polystyrenes was found to be about 17.7 kDa, while for standard proteins, the molecular weight size exclusion limit was higher, at approximately 25 kDa. The average pore diameter on a volume basis calculated from the pore network model changes from 8.5 nm (native… CONTINUE READING
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