Sulphatide in islets of Langerhans and in organs affected in diabetic late complications: a study in human and animal tissue

@article{Buschard1994SulphatideII,
  title={Sulphatide in islets of Langerhans and in organs affected in diabetic late complications: a study in human and animal tissue},
  author={Dr. K. Buschard and Knud Josefsen and Susanne V. Hansen and Thomas Horn and Marc Marshall and H{\aa}kan Persson and J. -E. M{\aa}nsson and Pam Fredman},
  journal={Diabetologia},
  year={1994},
  volume={37},
  pages={1000-1006}
}
Sulphatide has been found in rat islets of Langerhans and anti-sulphatide antibodies have been demonstrated in patients with insulin-dependent diabetes mellitus. Using a specific monoclonal antibody, Sulph I, directed against sulphatide, we investigated the in situ distribution of this glycolipid immunohistochemically; furthermore, the sulphatide concentration was determined in several organs and cells by thin-layer chromatography. The islets of Langerhans in all species examined, mouse, rat… CONTINUE READING

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