Sulphasalazine: A Review of 40 Years’ Experience

@article{Watkinson1986SulphasalazineAR,
  title={Sulphasalazine: A Review of 40 Years’ Experience},
  author={Dr Geoffrey Watkinson},
  journal={Drugs},
  year={1986},
  volume={32},
  pages={1-11}
}
SummarySulphasalazine, devised by Dr Nana Svartz for the treatment of ‘infective polyarthritis’,. has been used in the treatment of inflammatory bowel disease for more than 40 years. Many controlled trials have shown that sulphasalazine 4g daily will induce remissions in between one-half and three-quarters of patients with acute attacks of ulcerative colitis. When given in a dosage of 2g daily it will prevent relapses in quiescent colitis. Relapses are 5 times more likely in untreated patients… CONTINUE READING
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