Sulodexide suppresses inflammation in human endothelial cells and prevents glucose cytotoxicity.

@article{Ciszewicz2009SulodexideSI,
  title={Sulodexide suppresses inflammation in human endothelial cells and prevents glucose cytotoxicity.},
  author={Marta Ciszewicz and Alicja Polubinska and Artur Andrzej Antoniewicz and Katarzyna Sumińska-Jasińska and Andrzej K Breborowicz},
  journal={Translational research : the journal of laboratory and clinical medicine},
  year={2009},
  volume={153 3},
  pages={118-23}
}
Sulodexide is a mixture of heparin and dermatan sulfate with antithrombotic and profibrynolytic activity. Individual reports suggest the anti-inflammatory action of sulodexin. The goal of this study was to evaluate the effect of sulodexide on the release of the inflammatory mediators from endothelium in normal conditions and in cells chronically exposed to glucose. The experiments were performed on in vitro cultured human umbilical endothelial cells kept for 7 days in standard medium or in the… CONTINUE READING

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