Sulfur-dioxide-induced bronchitis in dogs. Effects on airway responsiveness to inhaled and intravenously administered methacholine.

@article{Shore1987SulfurdioxideinducedBI,
  title={Sulfur-dioxide-induced bronchitis in dogs. Effects on airway responsiveness to inhaled and intravenously administered methacholine.},
  author={Stephanie A. Shore and S T Kariya and Kenneth Anderson and W A Skornik and Henry A. Feldman and J W Pennington and John Godleski and Jeffrey M Drazen},
  journal={The American review of respiratory disease},
  year={1987},
  volume={135 4},
  pages={840-7}
}
Chronic bronchitis was induced in 7 dogs of mixed breed by chronic exposure to SO2 gas. Within the first 2 to 4 wk of exposure, the dogs developed cough and mucous hypersecretion, chronic airway obstruction (increased pulmonary resistance), and persistent lung inflammation as demonstrated by an increase in the number of neutrophils recovered in the… CONTINUE READING