Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents.

@article{Zhao2006SulforaphaneRI,
  title={Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents.},
  author={Jing Zhao and Nobuhide Kobori and Jaroslaw Aronowski and Pramod K Dash},
  journal={Neuroscience letters},
  year={2006},
  volume={393 2-3},
  pages={108-12}
}
Stroke is the third leading cause of death and disability in the United States. As several biochemical mechanisms have been proposed to contribute to stroke pathophysiology, treatments acting on multiple targets may be desirable. Sulforaphane (SUL), a naturally occurring isothiocyanate present in cruciferous vegetables, has been shown to induce the expression of multiple NF-E2-related factor-2 (Nrf2) responsive genes. In the present study, we demonstrate that systemically administered SUL can… CONTINUE READING