Sulforaphane induces cell type–specific apoptosis in human breast cancer cell lines

  title={Sulforaphane induces cell type–specific apoptosis in human breast cancer cell lines},
  author={Allison Pledgie-Tracy and Michele D. Sobolewski and Nancy E Davidson},
  journal={Molecular Cancer Therapeutics},
  pages={1013 - 1021}
Sulforaphane, an isothiocyanate found in cruciferous vegetables, has been shown to induce phase 2 detoxication enzymes and inhibit the growth of chemically induced mammary tumors in rats, although the exact mechanisms of action of sulforaphane are not understood. In this study, we evaluated the effects of sulforaphane on cell growth and death in several human breast cancer cell lines and examined the hypothesis that sulforaphane acts as a histone deacetylase (HDAC) inhibitor in these cell lines… 

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Sulforaphane-induced Cell Death in Human Prostate Cancer Cells Is Initiated by Reactive Oxygen Species*

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A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells.

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    Clinical cancer research : an official journal of the American Association for Cancer Research
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