Sulforaphane attenuates postnatal proteasome inhibition and improves spatial learning in adult mice.

@article{Sunkaria2018SulforaphaneAP,
  title={Sulforaphane attenuates postnatal proteasome inhibition and improves spatial learning in adult mice.},
  author={Aditya Sunkaria and Supriya Bhardwaj and Aarti Birendra Yadav and Avishek Halder and Rajat Sandhir},
  journal={The Journal of nutritional biochemistry},
  year={2018},
  volume={51},
  pages={69-79}
}
Proteasomes are known to degrade proteins involved in various processes like metabolism, signal transduction, cell-cycle regulation, inflammation, and apoptosis. Evidence showed that protein degradation has a strong influence on developing neurons as well as synaptic plasticity. Here, we have shown that sulforaphane (SFN) could prevent the deleterious… CONTINUE READING