Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells.

@article{Chiao2002SulforaphaneAI,
  title={Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells.},
  author={Jen-wei Chiao and F Chung and R R Kancherla and Tauseef Ahmed and Abraham Mittelman and C. Clifford Conaway},
  journal={International journal of oncology},
  year={2002},
  volume={20 3},
  pages={631-6}
}
The relation between the consumption of cruciferous vegetables and reduced prostate cancer occurrence has been documented, although the responsible phytochemicals are unknown. The effects of sulforaphane (SFN) which occurs as the precursor glucosinolate in broccoli and other cruciferous vegetables, and its metabolite N-acetylcysteine conjugate (SFN-NAC) on prostate cancer cells were investigated. SFN and SFN-NAC were analyzed with the androgen-dependent human prostate cancer LNCaP cell line… CONTINUE READING
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