Sulfonylguanidine Derivatives as Potential Antimelanoma Agents

@article{Baladi2020SulfonylguanidineDA,
  title={Sulfonylguanidine Derivatives as Potential Antimelanoma Agents},
  author={Tom Baladi and Nedra Hamouda-Tekaya and Leticia Christina Pires Gonçalves and S. Rocchi and C. Ronco and R. Benhida},
  journal={ChemMedChem},
  year={2020},
  volume={15}
}
Sulfonylguanidines are interesting bioactive compounds with a broad range of applications in the treatment of different pathologies. 2‐Aminobenzazole‐based structures are well employed in the development of new anticancer drugs. Two series of novel N‐benzazol‐2‐yl‐N′‐sulfonyl guanidine derivatives were synthesized with the sulfonylguanidine in either an extra‐ or intracyclic frame. They were evaluated for their antiproliferative activity against malignant melanoma tumor cells, thus allowing… Expand

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