Sulfonamides containing curcumin scaffold: Synthesis, characterization, carbonic anhydrase inhibition and molecular docking studies.

Abstract

Curcumin is a multi-functional pharmacologically safe natural agent with proven cytoprotective effects to healthy human cells. In this study, a new series of sulfonamides with curcumin scaffold were synthesized, characterized and investigated for their carbonic anhydrase isoenzyme I (human) and II (bovine) isoforms. The structures of newly synthesized… (More)
DOI: 10.1016/j.bioorg.2017.11.015

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Cite this paper

@article{Ahmed2017SulfonamidesCC, title={Sulfonamides containing curcumin scaffold: Synthesis, characterization, carbonic anhydrase inhibition and molecular docking studies.}, author={Mahmood Ahmed and Muhammad Abdul Qadir and Abdul Hameed and Muhammad Nadeem Arshad and Abdullah M. Asiri and Muhammad Muddassar}, journal={Bioorganic chemistry}, year={2017}, volume={76}, pages={218-227} }