Sulfite increases lipoperoxidation and decreases the activity of catalase in brain of rats

@article{Chiarani2007SulfiteIL,
  title={Sulfite increases lipoperoxidation and decreases the activity of catalase in brain of rats},
  author={F{\'a}bria Chiarani and Caren Serra Bavaresco and Carlos Severo Dutra-Filho and Carlos Alexandre Netto and Angela Terezinha Souza Wyse},
  journal={Metabolic Brain Disease},
  year={2007},
  volume={23},
  pages={123-132}
}
The main objective of this study was to investigate the in vitro effects of sulfite, a metabolite accumulated in isolated sulfite oxidase deficiency, on Na +, K +-ATPase activity and on some parameters of oxidative stress, namely thiobarbituric acid-reactive substances (TBARS) and catalase activity (antioxidant enzyme) in cerebral cortex, striatum and hippocampus from 10- and 60-day-old rats. Results showed that 500 μM sulfite significantly increased TBARS and reduced catalase activity in the… CONTINUE READING
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