Sulfide inhibition of and metabolism by cytochrome c oxidase.

@article{Nicholls2013SulfideIO,
  title={Sulfide inhibition of and metabolism by cytochrome c oxidase.},
  author={P. Nicholls and D. Marshall and C. Cooper and M. Wilson},
  journal={Biochemical Society transactions},
  year={2013},
  volume={41 5},
  pages={
          1312-6
        }
}
  • P. Nicholls, D. Marshall, +1 author M. Wilson
  • Published 2013
  • Chemistry, Medicine
  • Biochemical Society transactions
  • Hydrogen sulfide (H2S), a classic cytochrome c oxidase inhibitor, is also an in vitro oxidase substrate and an in vivo candidate hormonal ('gasotransmitter') species affecting sleep and hibernation. H2S, nitric oxide (NO) and carbon monoxide (CO) share some common features. All are low-molecular-mass physiological effectors and also oxidase inhibitors, capable of binding more than one enzyme site, and each is an oxidizable 'substrate'. The oxidase oxidizes CO to CO2, NO to nitrite and sulfide… CONTINUE READING
    83 Citations
    Cytochrome bd and Gaseous Ligands in Bacterial Physiology.
    • 18
    Bioenergetic relevance of hydrogen sulfide and the interplay between gasotransmitters at human cystathionine β-synthase.
    • 26
    • Highly Influenced
    Hydrogen Sulfide Biochemistry and Interplay with Other Gaseous Mediators in Mammalian Physiology
    • 29
    • Highly Influenced
    • PDF
    Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis
    • 9
    • PDF
    Hydrogen sulfide signaling in mitochondria and disease
    • 11
    Cystathionine-β-synthase: Molecular Regulation and Pharmacological Inhibition
    • 9
    • PDF

    References

    SHOWING 1-10 OF 23 REFERENCES
    Sulphide as an inhibitor and electron donor for the cytochrome c oxidase system.
    • 144
    Oxidation of sulphide by cytochrome aa3.
    • 42
    The effect of inhibitors on the oxygen kinetics of cytochrome c oxidase.
    • L. Petersen
    • Chemistry, Medicine
    • Biochimica et biophysica acta
    • 1977
    • 141
    Studies on Cytochrome Oxidase
    • 20
    • PDF