Sulfhydryl-mediated depression of ciliary activity: an adverse effect of acetylcysteine.

@article{Dreisin1979SulfhydrylmediatedDO,
  title={Sulfhydryl-mediated depression of ciliary activity: an adverse effect of acetylcysteine.},
  author={R B Dreisin and S R Mostow},
  journal={The Journal of laboratory and clinical medicine},
  year={1979},
  volume={93 4},
  pages={674-8}
}
Although N-acetyl-L-cysteine (Mucomyst) is an effective mycolytic, numerous investigations have failed to demonstrate a consistent improvement in pulmonary mechanics following its use. In order to determine whether its beneficial mucolytic activity might be counterbalanced by a deleterious direct effect on cilia, we studied its effect on the activity of… CONTINUE READING