Sulfation through the looking glass—recent advances in sulfotransferase research for the curious

@article{Coughtrie2002SulfationTT,
  title={Sulfation through the looking glass—recent advances in sulfotransferase research for the curious},
  author={M Coughtrie},
  journal={The Pharmacogenomics Journal},
  year={2002},
  volume={2},
  pages={297-308}
}
Members of the cytosolic sulfotransferase (SULT) superfamily catalyse the sulfation of a multitude of xenobiotics, hormones and neurotransmitters. Humans have at least 10 functional SULT genes, and a number of recent advances reviewed here have furthered our understanding of SULT function. Analysis of expression patterns has shown that sulfotransferases are highly expressed in the fetus, and SULTs may in fact be a major detoxification enzyme system in the developing human. The X-ray crystal… CONTINUE READING

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