Sulfated oligosaccharides: new targets for drug development?

@article{Kovensky2009SulfatedON,
  title={Sulfated oligosaccharides: new targets for drug development?},
  author={Jos{\'e} Kovensky},
  journal={Current medicinal chemistry},
  year={2009},
  volume={16 18},
  pages={
          2338-44
        }
}
Sulfated oligosaccharides display an important role in biological processes. They bind proteins through interactions mediated by highly specific sequences (heparin - antithrombin, heparan sulfate - growth factors / herpes simplex virus) or by electrostatic interaction between sulfate groups and cationic sites of proteins. Sulfated oligosaccharides are… CONTINUE READING