Sulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinus.

@article{Buresh2010Sulfatase1I,
  title={Sulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinus.},
  author={Rita A Buresh and Sheri L. Kuslak and Melissa A. Rusch and Chad M Vezina and Scott B. Selleck and Paul C. Marker},
  journal={Endocrinology},
  year={2010},
  volume={151 7},
  pages={3420-31}
}
The prostate gland develops from the urogenital sinus in response to circulating androgens. Androgens initiate and stimulate branching morphogenesis in the urogenital sinus via unknown mediators. Heparan sulfate proteoglycans are important extracellular molecules that sequester many growth factors in the extracellular matrix and facilitate signaling by some… CONTINUE READING