Sulfanilic acid: behavioral change related to azo food dyes in developing rats.

@article{Goldenring1982SulfanilicAB,
  title={Sulfanilic acid: behavioral change related to azo food dyes in developing rats.},
  author={James R Goldenring and D K Batter and Bennett A. Shaywitz},
  journal={Neurobehavioral toxicology and teratology},
  year={1982},
  volume={4 1},
  pages={43-9}
}
The effects of sulfanilic acid, a major azo food dye metabolite, were studied in normal developing rat pups and pups treated with 6-hydroxydopamine (60HDA). Chronic daily intraperitoneal injection of sulfanilic acid during the first postnatal month elicited hyperactivity and impaired shock escape performance in vehicle pups. No differences were noted in 60HDA treated rat pups receiving sulfanilic acid. These findings, which are similar to the results of our study of chronic administration of a… CONTINUE READING