Suicides and Suicide Attempts during Long-Term Treatment with Antidepressants: A Meta-Analysis of 29 Placebo-Controlled Studies Including 6,934 Patients with Major Depressive Disorder

@article{Braun2016SuicidesAS,
  title={Suicides and Suicide Attempts during Long-Term Treatment with Antidepressants: A Meta-Analysis of 29 Placebo-Controlled Studies Including 6,934 Patients with Major Depressive Disorder},
  author={C. Braun and T. Bschor and J. Franklin and C. Baethge},
  journal={Psychotherapy and Psychosomatics},
  year={2016},
  volume={85},
  pages={171 - 179}
}
  • C. Braun, T. Bschor, +1 author C. Baethge
  • Published 2016
  • Medicine
  • Psychotherapy and Psychosomatics
  • Background: It is unclear whether antidepressants can prevent suicides or suicide attempts, particularly during long-term use. Methods: We carried out a comprehensive review of long-term studies of antidepressants (relapse prevention). Sources were obtained from 5 review articles and by searches of MEDLINE, PubMed Central and a hand search of bibliographies. We meta-analyzed placebo-controlled antidepressant RCTs of at least 3 months' duration and calculated suicide and suicide attempt… CONTINUE READING
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