Suicide attempt using potassium tablets for congenital chloride diarrhea: A case report

  title={Suicide attempt using potassium tablets for congenital chloride diarrhea: A case report},
  author={Shigeo Iijima},
  journal={World Journal of Clinical Cases},
  pages={1463 - 1470}
  • S. Iijima
  • Published 26 April 2020
  • Medicine
  • World Journal of Clinical Cases
BACKGROUND Congenital chloride diarrhea (CCD) is a rare inherited disorder of intestinal electrolyte transport that results in a large wastage of electrolytes and water. Advances in substitution therapy using sodium chloride (NaCl) and potassium chloride (KCl) have dramatically improved survival for patients with CCD. Slow-release KCl is widely prescribed as a potassium supplement; however, it has also occasionally been used in suicide attempts, as potassium poisoning can generate life… 
3 Citations

Tables from this paper

Congenital chloride diarrhea clinical features and management: a systematic review

An analysis of a large population suggests the necessity of better strategies for the management of CLD, a rare autosomal recessive disorder characterized by watery diarrhea with a high level of fecal Cl−, metabolic alkalosis, and electrolyte alterations.

Potassium chloride overdose

  • Medicine
    Reactions Weekly
  • 2020



Sustained-Release Potassium Chloride Overdose

In both patients, the tablets were visualized on abdominal radiographs and the gastrointestinal tracts of both were successfully decontaminated using whole-bowel irrigation, and the abdominal radiograph appears to be useful in detecting sustained-release potassium tablets.

Poisoning with sustained release potassium.

A 27-year-old woman with anorexia nervosa took 60 tablets of Slow-K (sustained release potassium chloride 600 mg; 8 mmol each of K+ and Cl -) and soon started to vomit and was cyanosed with cold extremities, poor peripheral pulses, a regular pulse of 70/min and blood pressure 100/60 mmHg.

Successful whole bowel irrigation in self-poisoning with potassium capsules

A 28-year-old woman who was admitted on three occasions because of self-poisoning with potassium capsules and was successfully treated twice with WBI is presented.

Acute Oral Potassium Overdose: The Role of Hemodialysis

Hemodialysis should be considered in cases of potassium overdose with hemodynamic instability and significantly elevated serum potassium concentrations that do not respond promptly to medical therapy, particularly in cases with underlying renal dysfunction.

A Case of Slow-Release Potassium Chloride Overdose

An 86-year-old gentleman was brought to the emergency department after a massive overdose of slow-release potassium chloride and indapamide; there was no rebound of hyperkalaemia and his stay in the acute hospital was short.

Long-Term Clinical Outcome in Patients With Congenital Chloride Diarrhea

When early diagnosed and adequately treated, the long-term prognosis of CLD is favorable and a putative role of a primary anion exchange defect of SLC26A3 in male subfertility and the decline of renal function due to chronic dehydration deserve further characterization.

Congenital chloride diarrhea.

Specific disturbances of intestinal electrolyte transport are very rare, and the only ions known to be involved in specific malabsorption states are Zn+ (Rahanzadeh and Danzig 1974), Cu2+ (Danks et al. 1972) and C1-.

Congenital chloride diarrhoea. Clinical analysis of 21 Finnish patients.

The watery diarrhoea persists and increases slightly with age, though patients learn to live with their disease and to make an adequate social adjustment, and treatment prevents the renal lesions and the retarded growth and psychomotor development.