Suicide after deep brain stimulation of the internal globus pallidus for dystonia

@article{Foncke2006SuicideAD,
  title={Suicide after deep brain stimulation of the internal globus pallidus for dystonia},
  author={Elisabeth M. J. Foncke and P. R. Schuurman and Johannes D. Speelman},
  journal={Neurology},
  year={2006},
  volume={66},
  pages={142 - 143}
}
Deep brain stimulation (DBS) of the internal globus pallidus (GPi) has been reported to be beneficial and safe in selected dystonias.1 Behavioral, mood, and cognitive adverse effects occur only rarely with DBS of the GPi regardless of the underlying movement disorder. This is in contrast with the growing evidence that DBS of the subthalamic nucleus in Parkinson disease may induce serious adverse changes in behavior and mood, including suicide.2 Here, we report that 2 of 16 patients in our pilot… Expand
Deep brain stimulation for dystonia.
TLDR
This chapter provides a comprehensive analysis of the use of the treatment of the deep brain stimulation technique in various types of secondary dystonia, with little to moderate benefit in most cases, based on single cases or small series. Expand
Computational Modeling of Deep Brain Stimulation in the Globus Pallidus Internus
TLDR
Computational models are used to show how altering parameters such as electrode configuration, DBS lead placement and orientation, and stimulation voltage affects GPi modulation and activation of the cortical spinal tract (CST), the side-effect pathway. Expand
Deep brain stimulation for dystonia
TLDR
A literature analysis on DBS for dystonia is performed and the main results and limits for each subgroup of patients that may help in the selection of dystonic patients who will benefit from DBS are discussed. Expand
Pallidal deep-brain stimulation in primary generalized or segmental dystonia.
TLDR
Bilateral pallidal neurostimulation for 3 months was more effective than sham stimulation in patients with primary generalized or segmental dystonia and sustained improvement in all movement symptoms, the level of disability, and quality of life, as compared with baseline scores. Expand
Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease
TLDR
High-frequency deep brain stimulation of the subthalamic nucleus is a powerful method that is currently unchallenged in the management of Parkinson's disease, but its long-term effects must be thoroughly assessed. Expand
Bilateral pallidal deep brain stimulation in myoclonus-dystonia: our experience in three cases and their follow-up
TLDR
DBS improves significantly the Unified Myoclonus Rating Scale and Burke–Fahn–Marsden Dystonia Rating Scale in all three patients and is sustained over the years and no major adverse events were recorded. Expand
Quality of life outcomes after globus pallidus internus deep brain stimulation in idiopathic or inherited isolated dystonia: a meta-analysis
TLDR
This is the first meta-analysis that demonstrates significant benefits in HRQoL following DBS in patients with inherited or idiopathic isolated dystonia, and the benefits are greater for physical QoL domains compared with mental/psychological QOL. Expand
Deep brain stimulation for intractable tardive dystonia: Literature overview.
TLDR
The performed literature analysis indicates that bilateral GPi DBS is an effective treatment for disabling TD and the response of TD to bilateral GPo DBS may be very rapid and occurs within days/weeks after the procedure. Expand
Mood Effects After Deep Brain Stimulation for Parkinson's Disease: An Update
TLDR
No clear advantage of either target (STN vs. GPi) has been consistently found, both being effective and with a favorable profile on depression symptoms, but specific patients' characteristics or anatomical considerations can guide the neurosurgeon in the target choice. Expand
Pallidal stimulation for primary generalised dystonia: effect on cognition, mood and quality of life
TLDR
Calculation of a reliable change index suggested that deterioration in sustained attention on the PASAT was the only reliable change (worse after surgery) in cognition with GPi-DBS. Expand
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