Suicide Research

  title={Suicide Research},
  author={David M. Stoff and J. John Mann},
  journal={Annals of the New York Academy of Sciences},
  • D. Stoff, J. Mann
  • Published 1 December 1997
  • Psychology
  • Annals of the New York Academy of Sciences
This volume of the Annals contains the proceedings of a workshop on suicide research sponsored by the National Institute of Mental Health and the American Suicide Foundation. The workshop presented the latest research in suicide from preclinical, clinical neuroscience, and treatment perspectives. The preclinical section provides information on new methodologies in basic research that have promise for uncovering mechanisms that may underlie suicide. The clinical neuroscience section discusses… 

The Neurobiology and Genetics of Suicide and Attempted Suicide: A Focus on the Serotonergic System

Neurobiological underpinnings of suicidal behavior: Integrating data from clinical and biological studies

There is evidence that clinical, neurochemical, neuroendocrine, neurocognitive, and neurophysiological contributory factors may be useful as intermediate phenotypes in de- scribing putative causal pathways from genetics and early-life adversity to suicidal acts.

Rational Suicide, Hastened Death, and Self-Destructive Behaviors

This response article will elaborate on some of the more controversial issues raised by Werth and Holdwick (2000], as well as by Westefeld et al. (2000 [this issue]), and comment on the implications of these overviews for the training and clinical practice opportunities of counseling psychologists.

MRI correlates of suicide attempt history in unipolar depression

The struggle to prevent and evaluate: application of population attributable risk and preventive fraction to suicide prevention research.

Both PAR and PF are valuable instruments to inform development and evaluation of suicide prevention programs and the application of both concepts to suicide research and prevention is discussed.

Epidemiological link between low cholesterol and suicidality: A puzzle never finished

The aim of this contribution is to comprehensively update and critically review the epidemiological evidences and to discussions of the direction and methodological challenges for future investigations.

Increased suicide attempts in young depressed patients with abnormal temporal-parietal-limbic gray matter volume.

Crisis of Suicide: A Pastoral Psychological Approach

The issue of death is a common phenomenon among humans.  As common as it is however, the way one dies is a serious concern in the African setting, in particular.  Death by suicide is a detested

Neurobiological aspect of suicide; a review of low cerebrospinal 5 hydroxyindoleacetic acid concentration and prediction of suicidality

Finding an indicator that can point to a high risk group for suicide has long been a desirable aid for the prevention of completed suicides. The studies reviewed in this essay presume that a



Methodological Strategies in Suicide a

The purpose of this paper is to assess the contribution of various strategies in the search for understanding of suicide behavior and to recommend useful approaches for future research.


Introduction THIS REPORT has been written to pose the question: Could a biochemical test aid in the prediction of suicidal intent in depressed patients? To our knowledge the question has not been

Self-Destruction in the Promised Land: A Psychocultural Biology of American Suicide

In the present volume Kushner, a historian, has attempted a synthesis of these disparate influences to produce a unified theory of suicidology.

Further evaluation of urinary 17-hydroxycorticosteroids in suicidal patients.

THIS PAPER reports longitudinal steroid data on nine patients who subsequently committed suicide or who made a serious attempt and compares the significance of the elevations of these levels with 134

The dexamethasone suppression test in suicidal patients with unipolar depression.

Findings suggest that the tendency of endogenously depressed patients to attempt suicide is exacerbated by an underlying neurobiological disorder reflected by limbic-hypothalamic dysregulation and that depressed suicidal patients with abnormal DSTs represent a high-risk group for recurrence of suicidal behavior.

Reconciling the role of central serotonin neurons in human and animal behavior

  • P. Soubrié
  • Psychology, Biology
    Behavioral and Brain Sciences
  • 1986
Whether anxiety reduction or increased impulsivity is more likely to account for animal behavioral changes associated with decreased serotonergic transmission is investigated, as well as the effects of manipulating central serotonin in experimental anxiety paradigms in animals (punishment, extinction, novelty).

Neurochemical and electrophysiological events underlying stress-induced depression in an animal model.

  • J. WeissP. Simson
  • Psychology, Biology
    Advances in experimental medicine and biology
  • 1988
Findings from electrophysiological measurement of LC activity support the view that the LC is involved in stress-induced depression, and are consistent with a proposed mechanism that attributes behavioral disturbance in the model to disinhibition of LC neurons arising from subnormal activation of inhibitory alpha-2 receptors.

Dysfunctional attitudes and suicidal ideation in psychiatric outpatients.

The contributions of sets of dysfunctional attitudes for identifying and explaining suicidal ideation were overshadowed by a history of a past suicide attempt and hopelessness.

Suicide and the dexamethasone suppression test in unipolar depression.

The authors suggest that hypothalamic-pituitary-adrenal dysfunction is associated with a type of primary depressive illness that is more likely to involve suicide than are other types.

Failure of the urinary test for suicide potential. Analysis of urinary 17-OHCS steroid findings prior to suicide in two patients.

Urine 17-hydroxycorticosteroid determinations in a group of 36 depressed inpatients showed high mean urinary 17OHCS determinations, and patients had relatively low clinical ratings of suicidal behavior making such a test of great practical value.